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Description

IL-20 also caused tubular epithelial cells to die and increased mesangial cells production of pro-inflammatory molecules

47 , 8596 (2015b)

However, the lack of drug-like characteristics, such as poor target specificity and selectivity, high toxicity, several off-targets, severe side effects, poor metabolic stability, poor membrane permeability and rapid proteolysis, make this molecule fairly unsuitable candidates for therapeutic applications