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Dixon first discovered and named ferroptosis, the critical role of GPX4 in the inhibition of ferroptosis in his study has received widespread attention, mainly in the antioxidant axis system x c - -GSH-GPX4 ( c - is inhibited, obstruction of the cystine transport pathway can decrease GSH and GPX4, which can lead to cell death due to ongoing oxidative stress ( Figure 1A )

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But lets take a step back and talk about GHRH a bit more: Growth-hormone-releasing hormone (GHRH) is produced by the arcuate nucleus and induces the release of human growth hormone (hGH) by the anterior pituitary

10.1039/d1fo01154e 81 MaX.JinT.HanC.ShiN.LiangG.WenY.et al (2020)