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Baales-luna M, Figueroa-vega N, Marn-aragn CI, Perez-luque E, Ibarra-reynoso L, Gallardo-blanco HL, Lpez-aguilar I, Malacara JM (2020) Associations of nicotidamide- N -methyltransferase, FTO, and IRX3 genetic variants with body mass index and resting energy expenditure in Mexican subjects

That is why a better body composition strategy is usually focused on preserving or even improving tissue quality while body fat comes down

This can be used as evidence for your case

Crosstalk between STAT3, NF-B, and SMAD3 signaling STAT3, NF-B, and SMAD3 transcription factors are the main regulators of immune functions involving both the differentiation of immune cells and the modification of their different phenotypes and properties