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EGCG-Zn treatment significantly downregulated the expression of multiple key proinflammatory genes in the MAPK pathway (such as Fos, Jun, and Mapk8), suggesting that it could alleviate radiation-induced tissue injury by inhibiting MAPK-mediated inflammatory amplification and apoptotic signaling

Use of an antiviral mouthwash as a barrier measure in the SARS-CoV-2 transmission in adults with asymptomatic to mild COVID-19: a multicentre, randomized, double-blind controlled trial

As we seek to develop more potent PINK1 inhibitors based on these scaffolds, the challenge will be to reduce the potency against other kinases to achieve sufficient selectivity for their use as chemical probes

The results showed both genotypes shared enrichment in metabolic pathways, phenylpropanoid biosynthesis, and glutathione metabolism though the extent and significance of gene enrichment varied (Fig