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In later stages (lower panel), intact T cells are observed breaching the plasma membrane of myofibroblast-like cells and penetrating the cytoplasm toward the nuclear lamina (red arrow), accompanied by pronounced organelle damage

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Theyre relatively accurate, but generally not as sensitive as more sophisticated lab testing methods

Key Takeaway: Tirzepatides dualagonist profile makes it a powerful RUO tool for dissecting metabolic pathways and appetite regulation in preclinical models