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This acid is decarboxylated to hypotaurine by the cysteine sulfinic acid decarboxylase, which is finally oxidized to taurine by hypotaurine dehydrogenase

Cysteine depletion, which results in the intracellular exhaustion of glutathione, serves as a preliminary feature of the mechanism and triggers ferroptosis ( The biological features of ferroptosis are distinguished by the aggregation of iron and ROS, which reduces the level of cystine uptake and consumes GSH to inhibit the activities of system xc- and GPX4

Endogenous genes in pigs can be edited through CRISPR Cas9 combined with somatic cell nuclear transfer (SCNT) to produce knock-out or knock-in models