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Here, we have reported the discovery of two allosteric ME2 inhibitors, EA and MDSA, that are capable of inhibiting ME2 activity and thus decreasing the production of cellular pyruvate, NADH, and ATP

A library of nucleic acids encoding a plurality of modified antigen binding sites, wherein the modified antigen binding sites are derived from a first nucleic acid comprising a sequence encoding a first antigen binding site, made by a method comprising the following steps: (a) providing a first nucleic acid encoding a first antigen binding site

Elution of anti-spectrin antibodies from red cells in homozygous b-thalassemia

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