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Although studies on mitochondrial damage-associated energy metabolism and glutathione downstream signal molecules are needed, these findings may be presented as additional evidence that the intracellular uptake of glutathione can alter the redox state of cells and thereby regulate cellular antioxidant signaling pathways

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Free Radic Biol Med 19:911918 Galvez J, Coelho G, Crespo ME, Cruz T, Rodriguez-Cabezas ME, Concha A, Gonzalez M, Zarzuelo A (2001) Intestinal anti-inflammatory activity of morin on chronic experimental colitis in the rat

Therefore, OS does not seem to play a role after the very early moment of irradiation