glutathione plasticity Depletion in Mitochondrial Diseases An Open-Label Case Series of

5.7 Inflammatory bowel disease Inflammatory Bowel Disease (IBD), encompassing Crohns disease (CD) and ulcerative colitis (UC), is a chronic inflammatory disorder of the gastrointestinal tract driven by a combination of genetic susceptibility, immune dysregulation, and gut microbiota alterations (165)

FIGURE 1 The prevalence of DED, which surged to as high as 61.0% during the COVID-19 pandemic (Ji et al., 2023), underscores the influence of increased exposure to visual display terminals and widespread mask usage during the pandemic, which likely exacerbated the condition by decreasing blink frequency and increasing thermal air currents over the ocular area, thus enhancing tear evaporation rates (Uwimana et al., 2022

Research has shown that GHRH administration promotes slow-wave sleep (deep sleep) and enhances the natural nocturnal GH surge (10)

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