glutathione in er lumen

glutathione in er lumen The antioxidant plays a key role protein folding The team discovered a few years ago that if glutathione levels aren't precisely maintained in mitochondria, all systems fail. On the heels SLC33A1-mediated glutathione transport regulates ER

Name: glutathione in er lumen The antioxidant plays a key role protein folding The team discovered a few years ago that if glutathione levels aren't precisely maintained in mitochondria, all systems fail. On the heels SLC33A1-mediated glutathione transport regulates ER
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SLC33A1 mediated glutathione transport regulates ER redox balance and function Nature Cell Biology Endoplasmic reticulum stress: molecular mechanism and therapeutic targets Signal Transduction and Targeted Therapy 3.2 The Endomembrane System I The Endoplasmic Reticulum and Golgi Apparatus Cell & Molecular Biology Cellular Compartmentalization, Glutathione Transport and Its Relevance in Some Pathologies

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[184] High levels of soluble misfolded mutant SOD1 species and larger detergentinsoluble mutant SOD1 protein aggregates accumulate selectively in neuronal regions most affected by the ALS disease process, indicating SOD1 selfassembly is associated with severe motor neuron degeneration.[ 13 , 156 ] Accordingly, when mutant protein expression is low and SOD1 accumulation is absent, ALS motor symptomology is not observed