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The mood stabilizers lithium and valproate attenuate a series of METH-induced changes, such as reduction of mitochondrial Cyt c, the mitochondrial anti-apoptotic Bcl-2/Bax ratio, activity of mitochondrial Cyt c oxidase, and the expression of several proteins related to the apoptotic pathway

Glutathione is naturally made in the body using three amino acids, which are cysteine, glycine, and glutamic acid

To be noted, one highlight of this study is the experiments on cell identification and enrichment of whole-brain tissue samples, demonstrating their strategy achieved around 90% cell specificity of selective transfection with no extra use of a cell-specific promoter

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