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MHR Basic Sci Reprod Med 20(10):948959 Los M, Craen MVd, Penning LC, Schenk H, Westendorp M, Baeuerle PA, Drge W, Krammer PH, Fiers W, Schulze-Osthoff K (1995) Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis

The vascular smooth muscle cell: a therapeutic target in type 2 diabetes

Yet, it is unknown if this formulation would exert primarily local effects on the digestive system, or if it would work systemically

Similarly, this is also seen in the setting of many chronic diseases such as metabolic syndrome and diabetes [3,4], atherosclerosis and cardiovascular disease [5], chronic kidney disease [6], neurodegenerative conditions such as Alzheimers disease and Parkinsons disease [7-9], as well as autoimmune diseases [10], cancer [11] and chronic infections such as human immunodeficiency virus [12]