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In contrast, -catenin activates key glycolytic enzymes such as HK2 and PKM2 and promotes the activation of the NLRP3 inflammasome in macrophages

J Cell Mol Med 24(5):29012916 Jia K, Zhang Y, Luo R, Liu R, Li Y, Wu J, Xie K, Liu J, Li S, Zhou F, Li X (2023) Acteoside ameliorates hepatic ischemiareperfusion injury via reversing the senescent fate of liver sinusoidal endothelial cells and restoring compromised sinusoidal networks

In September 2023, the FDA listed BPC-157 as a Category 2 bulk drug substance

14 However, the data are confounded by past or concomitant use of phototherapy or other immunosuppressive agents