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Although no site-specific ADCs are found in the current eleven FDA-approved products (Adcetris , Besponsa , Blenrep [initiating the process for market withdrawal], Enhertu , Kadcyla , Mylotarg , Padcev , Polivy , Tivdak , Trodelvy , Zynlonta ), their TAA-targeting antibody scaffolds can presumably be further engineered for multi-payload conjugations to achieve better drug efficacy by utilizing the abovementioned site-specific conjugation technologies

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