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Name: klow injection site redness Reactions: Symptoms, Treatment, and Prevention Understanding Injection Site Reactions with
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ROS are generated within the biological system to modulate the cellular activities such as cell survival, stressor responses, and inflammation (He and Zuo, 2015

Kolchina N, Khavinson V, Linkova N, et al

6B and Supplementary Fig

Mechanistically, SYVN1 binds to HMGB1, promoting its ubiquitination and degradation and alleviating SCIRI in rats by downregulating HMGB1 and activating the Nrf2/HO-1 pathway