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Although dark spots and uneven skin tone are among the most common skin concerns affecting women, facial pigmentation treatment is now more advanced and effective than ever, with targeted solutions designed to address pigmentation at its source to improve skin clarity

Your Visit What to expect at your first appointment Most patients walk out with medication on the same visit

In high SAMe conditions methylation of hairpin 1 (hp1) of the MAT2A 3UTR promotes intron retention and nuclear degradation whilst low SAMe levels promote the enhanced binding of METTL16 to the hp1 of MAT2A 3UTR leading to increased splicing and MAT2A translation[71,72]