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[DOI] [PMC free article] [PubMed] [Google Scholar] 68.Yang XD, Huang B, Li M, Lamb A, Kelleher NL, Chen LF

Although PYC has been shown to reduce CRP levels, existing trials are limited by small sample sizes (e.g., five studies totaling approximately 324 participants in a CRP meta-analysis), high heterogeneity (I 2 99%), and variability in dosing regimens, treatment duration, and study populations ( Similarly, although PYCs anticancer effects have been demonstrated in multiple cell lines and preclinical models, translational data remain limited

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