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In the presence of divalent cations such as Mg 2+ or Mn 2+ , the terminal phosphate from ATP is transferred to glutamate resulting in -glutamyl phosphate, which is subsequently attacked by ammonia to form glutamine (Fig

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We hypothesize that blocking calcium-permeable channels that are sensitive to pressure or its biomechanical corollaries (such as tensile stretch) might result in even more significant injury amelioration in hypertensive eyes