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Seek out a primary care physician, integrative or functional medicine provider for an appointment

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Reassess benefits and risks within one day after prescribing opioids, including checking the prescription drug monitoring database

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Excessive NAM depletion directly reduces the substrate supply for NAD+ synthesis, leading to decreased intracellular NAD+ levels

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[PMC free article: PMC3985831] [PubMed: 24598885] 24

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