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Thus, iron metabolism might be involved in regulating the injury of RGCs under ph-IOP

However, the oxidative stress generated by excessive ROS may lead to destructive consequences for mitochondria, other organelles, and cellular pathways, eventually leading to cell death [49]

It is worth noting that the co-existence of adipocytes and cancer cells enhances both ketogenesis in adipocytes and ketolytic activity in breast cancer cells (276)