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doi: 10.1002/cbf.3351

Altering the intestinal microbiota of mice through a high-fat diet (HFD) leads to a decrease in hematopoietic stem cells, which can be achieved by transferring feces from mice on HFD to normal mice (Luo et al., 2015)

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In animal models, DFO treatment decreased AD hallmarks, iron overload, iron-induced kinase activity [cyclin-dependent kinase 5 (CDK5), glycogen synthase kinase 3 (GSK3)], mitochondrial dysfunction, synaptic loss, and neuronal damage (Sripetchwandee et al., 2016)