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An earlier controlled study (Coviello 2005) showed that low-dose HCG maintained intratesticular testosterone in a dose-dependent way when the body's own gonadotropins were suppressed the mechanistic basis for using it during testosterone therapy

Retatrutide is a more recently developed triple agonist peptide, targeting GLP-1 (glucagon-like peptide-1), GIP (glucose-dependent insulinotropic polypeptide), and glucagon receptors simultaneously

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