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But my perspective is, look, everyone should always go for the low hanging fruit first and then, you know, start taking a crack at the deeper, more idiosyncratic things when you run it, when you hit a wall

New Results doi: Abstract The abbreviation PDK1 may refer to two different proteins: pyruvate dehydrogenase kinase 1 and 3-phosphoinositide-dependent protein kinase 1

doi: 10.3389/fcimb.2025.1733264 Received 30 October 2025 Revised 25 November 2025 Accepted 29 November 2025 Published 16 December 2025 Volume 15 - 2025 Edited by Akansha Singh, University of Texas Southwestern Medical Center, United States Reviewed by Cristin Coman, National Institute of Medical-Military Research and Development, Romania Rahul Ahuja, University of Colorado, United States Updates Copyright 2025 Resta, Tal, Conte, Calcagnile, Bucci and Alifano

The activities of SOD, CAT, and APX scavenge ROS, which otherwise cause oxidative damage, and then convert them to harmless H 2 O and O 2 (Shekhawat et al., 2010)