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Garcia-Esquinas E Article: JAMA NETWORK OPEN

Apparently, the hierarchical sandwich-type core/shell structure of AuNP core/vertical ADC interlayer/horizontal YTDB outer layer is assembled, generating the protective cavity in the interlayer for gene drug loading

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Proper aseptic technique includes: Cleaning the vial septum with appropriate antiseptic (typically 70% isopropyl alcohol) before each access Using a sterile needle and syringe for each withdrawal Maintaining sterile conditions throughout the preparation process Avoiding touch contamination of the vial septum or needle Following institutional or professional protocols for multi-dose vial management Consequence of Improper Technique: Failure to maintain aseptic technique can result in microbial contamination of the vial contents, potentially leading to serious infection if contaminated solution is administered