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The same caution applies to other compounds discussed in the context of mitochondrial protection, including matrine, pinocembrin, -lipoic acid, and related pleiotropic agents: although they may improve mitochondrial performance and attenuate ER stress, inflammation, or redox imbalance, they should be regarded primarily as broad stress-response modulators rather than selective regulators of organelle contact sites

10.7150/ijbs.72707 Int J Biol Sci

Why Patients Love the BPC 157 and TB 500 Combination Many people who start on the BPC 157 and TB 500 combination notice results faster than they expect

The genes for these and other phase II enzymes contain AREs and are therefore under the control of Nrf2 (see Antioxidant activity)