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doi: 10.3389/fimmu.2022.762580 121 ZelanteTIannittiRGCunhaCDe LucaAGiovanniniGPieracciniGet al

These outcomes highlight challenges such as inter-individual differences (what works in one persons gut may not in anothers), timing (intervening too late in disease may limit benefits), and the need for biomarkers to identify who is most likely to respond

Protein Pept Lett

The ER/mitochondrial crosstalk is provided by involvement of Bax, Bak, Bim, or PUMA, as well as MOMP-regulating Ca 2+ signaling and communication through mitochondria-associated ER membranes (MAMs) [90, 91]