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[DOI] [PMC free article] [PubMed] [Google Scholar] 45.Kunierczyk P, Majorczyk E

Differences in the response of drugs in animals and in man, and, in particular, differences in drug metabolism, bioactivation and disposition, stimulated the search for human relevant experimental models that could replace the use of animals for human safety assessment and prediction

Closer evaluation of the protein classification list (Extracellular Matrix Protein) revealed unique enrichment of Latent Transforming Growth Factor Beta Binding Protein 1 (LTBP1) in ExerVs, a factor that maintains TGF1 in a latent or inactive state 48

PMCID: PMC3601092