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Circumventing the cellular defenses against ferroptosis in lung cancer cells while maintaining normal physiological functions is crucial for the effective treatment of lung cancer

Aydin, T., Karacan, I., Demir, S

10.22365/jpsych.2022.073 Psychiatriki 8 AnY.FengL.ZhangX.WangY.WangY.TaoL.et al (2019)

However, several orally bioavailable PROTACs have been reported, most of them recruiting the cereblon E3 ligase, with some advancing into clinical studies (e.g., ARV-110 or ARV-471)