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doi: 10.1016/bs.apcsb.2019.02.001 283 HoheneggerMWaldhoerMBeindlWBingBKreimeyerANickelPet al

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To illustrate, we can point to several double-blind, randomized controlled trials that otherwise failed to support its therapeutic potential for specific diseases

It summarizes key strategies for enhancing MSC adaptability and therapeutic efficacy and proposes standardized parameters for optimizing clinical applications, aiming to provide a theoretical basis and path support for advancing the clinical translation of stem cell therapy in intervertebral disc regeneration