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Although direct evidence connecting phytochemicals to incretin-mediated neuroprotection in PD is still emerging, it is biologically plausible that phytochemical-driven DPP-IV inhibition or incretin stimulation could enhance neuronal energy metabolism, mitochondrial function, and anti-inflammatory signaling, thereby protecting dopaminergic neurons

Adams, I., et al., Targeting hepatic sulfane sulfur/hydrogen sulfide signaling pathway with -lipoic acid to prevent diabetes-induced liver injury via upregulating hepatic CSE/3-MST expression