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Higher concentration: mixing to 10 mg/mL keeps injection volumes small even at the top of the range useful when titrating toward 4.5 mg, the dose linked with the largest weight reductions in early trials [4]

We simulated aggregated CY 2026 hospital outlier payments using these costs for several different fixed-dollar thresholds, holding the 1.75 multiple-threshold constant and assuming that outlier payments will continue to be made at 50 percent of the amount by which the cost of furnishing the service would exceed 1.75 times the APC payment amount, until the total outlier payment equaled 1.0 percent of aggregated estimated total CY 2026 OPPS payments

Individual experiences may vary depending on lifestyle factors, baseline vitamin levels, and overall health