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( Vicia faba plants

These three biological states appear to be able to influence one another in a self-sustaining cycle (Nguyen et al., 2011) forming a neurotoxic triad. Figure 1 illustrates the self-sustaining interaction between excitotoxicity, oxidative stress, and inflammation (which are reviewed below), while also presenting some nutritional deficiencies which can fuel the triad

the FY 2019 IPPS/LTCH PPS final rule (83 FR 41623)

Understanding these deep cellular mechanisms is crucial when exploring how a doctor diagnoses Long COVID and why one-size-fits-all treatments often fail