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Signs that may indicate the need for such Treatment include: Hyperpigmentation: Noticeable dark patches or uneven skin tone can suggest an excess of melanin, making skin lightening beneficial

11 subjects had withdrawn from the study before supplementation was started

Treatment with the drug demonstrated statistically significant improvements in biochemical response compared to UDCA alone, Christelle Huguet, executive vice president and head of research and development at Ipsen, said in a press release