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By blocking the NADPH redox cycle, Nrf2 mitigates the inhibitory effect of FSP1, thus limiting its ability to induce ferroptosis (82)

253 A pivotal event in CRC development is the accumulation of oncogenic -catenin due to disruptions in its regulatory pathways

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[DOI] [PubMed] [Google Scholar] 95.Rodan L.H., Hauptman M., DGama A.M., Qualls A.E., Cao S., Tuschl K., Al-Jasmi F., Hertecant J., Hayflick S.J., Wessling-Resnick M., et al