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NDP-alpha-MSH) is a linear analog of alpha-MSH with Nle4 and D-Phe7 substitutions that confer increased MC1R binding affinity and metabolic stability compared to native alpha-MSH

Amelanotic melanoma accounts for 5-35% of oral melanomas

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Vemurafenib is an orally available, small-molecule, selective BRAF V600E kinase inhibitor, and its indication is limited to patients with a demonstrated BRAF V600E pathogenic variant by an FDA-approved test.[15] Dabrafenib Dabrafenib is an orally available, small-molecule, selective BRAF inhibitor that was approved by the FDA in 2013