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Zhang ZH, Zeng XA, Brennan CS, Ma HL, Aadil RM

Purifications were conducted by preparative RP-HPLC, eluting with a linear gradient (20 ml min 1 ) and using a binary solvent system consisting of H 2 O:MeCN:TFA (buffer A, 95:5:0.1

Aptamers are thermostable and chemically stable, and chemical modification can enable their conjugation to nanoparticles, drugs, or other nucleic acid drugs to improve cellular uptake

One-way ANOVA followed by Tukeys test was performed to test significant variations on survival time, change in body weight, antioxidants status, lipid peroxidation, tumor volume, cytotoxicity, hematological parameters, and activities of serum enzymes