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This is a direct biomarker of total serum lipid peroxidation, which are the products of the chemical damage done by oxygen free radicals to the polyunsaturated fatty acids of cell membranes

doi: 10.2147/DMSO.S300015 7 StojanovichLMarisavljevichD

Peer review Peer review information Nature Protocols thanks Nigel Forest Reuel and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

374 In the short term, n-3 PUFA consumption increases nitric oxide (NO) production, mitigates vasoconstrictive responses to norepinephrine and angiotensin II, enhances vasodilatory responses, and improves arterial compliance