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Some reasons for vitamin B12 deficiency are: Gastritis: It refers to stomach lining inflammation and is one of the most common causes of the condition

ATF6 is involved in ER stress-induced autophagy by promoting autophagy through upregulating the expression of CHOP (Motawi et al., 2022)

The authors proposed that continual stimulation of sensory nerves during an exacerbation might have led to neuropeptide depletion, thus accounting for the decreased content