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This redox imbalance promotes enhanced expression of T2-associated proteins, leaving the cells vulnerable to oxidatively induced cell death and, potentially, to asthma exacerbations

Brown fat AKT2 is a cold-induced kinase that stimulates ChREBP-mediated de novo lipogenesis to optimize fuel storage and thermogenesis

doi: 10.3390/ijms232315395 181 RichardsJ

However, as the disease progresses, uncontrolled necroptosis exacerbates mucosal inflammation and contributes to the transformation of inflammation into cancer (119)