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In these cases, plant susceptibility may be linked to the efficiency of the antioxidant system in controlling ROS to prevent excessive cell death and facilitate pathogen colonization (Tvora et al., 2021)

In animal models, exposure to lead acetate led to inhibition of ALAS in blood, activation of plasma CAT, elevation of MDA and GSSG, reduction in the level of plasma GSH, and an increase in oxygen free radicals ( Figure 1 ) [64]