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Supplementary material The Supplementary Material for this article can be found online at: References 1 AdamsP

J.DelgadoT.TovarY

Methotrexate or valproic acid alone or in combination induced significant increase in tissue catalase and glutathione reductase with significant decrease in tumor volume, tissue malondialdehyde, cholesterol and tumor necrosis factor- and alleviated the histopathological changes with significant increase in p53 expression and apoptotic index compared to solid Ehrlich carcinoma group