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Clear communication and diligent checks are crucial to keeping the patient safe and achieving the optimal outcome

Figure 2 illustrates how these interventions map onto the immunometabolic pathways: e.g., scavenging mtDNA, inhibiting inflammasomes, boosting mitophagy, providing healthy mitochondria, and improving immune cell metabolism at various points in the cascade

There is a large amount of evidence showing the efficacy of anti-VEGF therapy in DME

The dysregulated NAD + /NADH ratio, together with the absence of SIRT3, may cause cell cycle and mitosis arrest, and mediate metabolic changes in aging by activating AMPK to initiate senescence via the classical p53 pathway