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Patients often wake up feeling just as exhausted as when they went to sleep, a phenomenon known as non-restorative sleep

A detailed understanding of the distinct pathophysiological mechanisms and redox imbalances underlying each neurodegenerative disorder is crucial for advancing personalized therapeutic strategies, enabling interventions tailored to the specific cellular vulnerabilities and molecular drivers of each disease

Fat atrophy is reported in patients with Ehers-Danlos syndrome with mutations in ZIP13 function loss

Comparatively fewer studies have globally analyzed PTM distributions across organelles to reveal PTM-specific localizations and/or functions, though some studies have begun to shed light on this aspect of regulation (Zhou et al., 2010