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Important Safety Reminders Medical Supervision Required: AOD-9604 should only be used under qualified medical supervision Baseline and monitoring laboratory testing is recommended Individual contraindications and health status must be evaluated AOD-9604 is not FDA-approved for any indication Contraindications and Precautions: Pregnancy and breastfeeding (no safety data available) Active malignancy (discuss with oncologist) Pediatric use (not studied in children) Significant organ dysfunction (limited safety data) Report Concerns: Any unexpected symptoms or adverse effects should be reported to your healthcare provider promptly

Another important finding of our study was that postnatal vB12 treatment of Tbx1 +/ mice rescued the PPI deficit previously reported (2)

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The research on this topic is not sufficient enough to directly correlate the B12 vitamin and depression, but studies have shown that the increase in B12 can help prevent depression and ease its symptoms