glutathione stability Frontiers glutathione s transferase stability The

Modulation of IMS redox pathways influences E GSH [IMS] only to a minor extent Due to its proximity to the respiratory chain, the IMS glutathione pool might be influenced by the activity of the respiratory chain, for example, by release of reactive oxygen species (ROS)

With respect to safety, the compounds do not trigger hemolysis or other signs of toxicity in mice

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This creates a regional pattern that does not resemble the results obtained with any other serotonergic drug using this method. Why This Matters This nigrostriatal focus is mechanistically intriguing because these regions are heavily involved in motor control, reward processing, and motivation