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229,230 Interestingly, in a patient with SCO2 mutations who presented with severe hypertrophic cardiomyopathy, Cu-histidine supplementation has been reported to improve heart function, showing attenuated cardiomyopathy as well as the normalization of blood pressure

the relevance of this finding to humans remains uncertain, and UK SmPCs for licensed GLP-1 analogues note this as a precautionary concern rather than a confirmed human risk [6] Sermorelin's risks include fluid retention, joint discomfort, and potential stimulation of pre-existing growth-dependent pathologies

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