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[DOI] [PubMed] [Google Scholar] 73.Zhang Y., Liu Y., Zou J., Yan L., Du W., Zhang Y., Sun H., Lu P., Geng S., Gu R., et al

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The collective outcome of the dysfunctions described aboveenergy crisis, oxidative damage, and a diminished functional mitochondrial poolprecipitates a fundamental shift in cellular metabolism. OA chondrocytes undergo significant metabolic reprogramming