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Description

It acts on the polycyclic aromatic hydrocarbon receptor (AHR) and up-regulates the expression of ALDH1A3

View Study [4]"Development of Cagrilintide, a Long-Acting Amylin Analogue" Kruse T et al., 2021 Finding: Describes the medicinal chemistry development of cagrilintide, explaining how lipidation extended the half-life from minutes (pramlintide) to approximately one week while maintaining receptor activity