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Breakdown of glutathione, oxidized glutathione and glutathione S-conjugates happens upon uptake into the vacuole but can also take place in the cytosol and apoplast 56

In hepatic and renal tissues, BHMT provides a compensatory remethylation pathway that becomes particularly relevant when folate-dependent remethylation is limited, underscoring tissue-specific buffering within the one-carbon network

Results GSH levels in the ELF, plasma, and liver were decreased by as much as 50% during the 5 h CS exposure period whereas the lung GSH levels were unchanged

Outcomes from studies of antineutrophil cytoplasm antibody associated vasculitis: a systematic review by the European League against Rheumatism systemic vasculitis task force