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Description

Simultaneously, Akt phosphorylates the FOXO family of transcription factors (FOXO1, FOXO3, FOXO4), sequestering them in the cytoplasm and preventing them from transcribing the atrogenes MuRF1 and atrogin-1/MAFbx that drive ubiquitin-proteasome-mediated muscle protein breakdown

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Autophagy 5 , 795804 (2009)

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Chromatin silencing and activation by Polycomb and trithorax group proteins

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